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Reimagining Lymphatic Access

We introduce a breakthrough port-a-cath–style device specifically designed for congestive heart failure patients. This innovation is tailored to the lymphatic system, offering a novel approach to thoracic duct access while remaining grounded in empirical research and clinical safety.

About Us

We are EAZI Solutions, four Biomedical Engineering students from UT San Antonio with the goal of improving upon a device that will be used to remove excessive fluid. One of our target populations being congestive heart failure patients who are refractory to diuresis. 
 

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Current Projects:

Thoracic Duct Drainage Port for Lymphatic Volume Overload in Heart Failure Patients 

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Current approaches to managing fluid overload in CHF are primarily drug-based, relying on diuretics to remove excess fluid; however, 25–30% of patients develop resistance, limiting effectiveness. Previous strategies, including invasive surgeries and needle-based thoracic duct access, carried high risks of infection and were associated with significant mortality.

Clinical Interventions

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The lymphatic system is a complex, low-pressure network of vessels that collects interstitial fluid and returns it to circulation. The thoracic duct, its largest vessel, runs from the cisterna chyli to the neck, draining most of the body and emptying into the left subclavian–jugular vein junction.

Intricate Anatomy

Lymphatic System

Function  |  Anatomy  |  Limitations

In congestive heart failure (CHF), elevated central venous pressure increases fluid filtration into tissues while impairing lymphatic drainage. Over time, inflammation and vessel dysfunction reduce lymphatic transport capacity, leading to fluid accumulation, edema, and worsening organ congestion.

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Dysregulation

Intricate Anatomy

Dysregulation

Lack of Research

The lymphatic system is underexplored due to its complex anatomy and limited imaging options. While animal studies show that relieving lymphatic overload improves symptoms, poor visualization with conventional imaging has hindered human research and clinical translation.

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Clinical Interventions

The lymphatic system is a complex, low-pressure network of vessels that collects interstitial fluid and returns it to circulation. The thoracic duct, its largest vessel, runs from the cisterna chyli to the neck, draining most of the body and emptying into the left subclavian–jugular vein junction.

Current approaches to managing fluid overload in CHF are primarily drug-based, relying on diuretics to remove excess fluid; however, 25–30% of patients develop resistance, limiting effectiveness. Previous strategies, including invasive surgeries and needle-based thoracic duct access, carried high risks of infection and were associated with significant mortality.

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